Contemporary clinical profile and outcome of prosthetic valve endocarditis
Identifieur interne : 009667 ( Main/Exploration ); précédent : 009666; suivant : 009668Contemporary clinical profile and outcome of prosthetic valve endocarditis
Auteurs : Andrew Wang [États-Unis] ; Eugene Athan [Australie] ; Paul A. Pappas [États-Unis] ; Vance G. Jr Fowler [États-Unis] ; Lars Olaison [Suède] ; Carlos Pare [Espagne] ; Benito Almirante [Espagne] ; Patricia Munoz [Espagne] ; Marco Rizzi [Italie] ; Christoph Naber [Allemagne] ; Mateja Logar [Slovénie] ; Pierre Tattevin [France] ; Diana L. Iarussi [Italie] ; Christine Selton-Suty [France] ; Sandra Braun Jones [Chili] ; José Casabe [Argentine] ; Arthur Morris [Nouvelle-Zélande] ; Ralph Corey [États-Unis] ; Christopher H. Cabell [États-Unis]Source :
- JAMA, the journal of the American Medical Association [ 0098-7484 ] ; 2007.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Médecine.
English descriptors
- KwdEn :
Abstract
Context Prosthetic valve endocarditis (PVE) is associated with significant mortality and morbidity. The contemporary clinical profile and outcome of PVE are not well defined. Objectives To describe the prevalence, clinical characteristics, and outcome of PVE, with attention to health care-associated infection, and to determine prognostic factors associated with in-hospital mortality. Design, Setting, and Participants Prospective, observational cohort study conducted at 61 medical centers in 28 countries, including 556 patients with definite PVE as defined by Duke University diagnostic criteria who were enrolled in the International Collaboration on Endocarditis-Prospective Cohort Study from June 2000 to August 2005. Main Outcome Measure In-hospital mortality. Results Definite PVE was present in 556 (20.1 %) of 2670 patients with infective endocarditis. Staphylococcus aureus was the most common causative organism (128 patients [23.0%]), followed by coagulase-negative staphylococci (94 patients [16.9%]). Health care-associated PVE was present in 203 (36.5%) of the overall cohort. Seventy-one percent of health care-associated PVE occurred within the first year of valve implantation, and the majority of cases were diagnosed after the early (60-day) period. Surgery was performed in 272 (48.9%) patients during the index hospitalization. In-hospital death occurred in 127 (22.8%) patients and was predicted by older age, health care-associated infection (62/203 [30.5%]; adjusted odds ratio [OR], 1.62; 95% confidence interval [Cl], 1.08-2.44; P=.02), S aureus infection (44/128 [34.4%]; adjusted OR, 1.73; 95% Cl, 1.01-2.95; P=.05), and complications of PVE, including heart failure (60/183 [32.8%]; adjusted OR, 2.33; 95% Cl, 1.62-3.34; P<.001), stroke (34/101 [33.7%]; adjusted OR, 2.25; 95% Cl, 1.25-4.03; P=.007), intracardiac abscess (47/144 [32.6%]; adjusted OR, 1.86; 95% Cl, 1.10-3.15; P=.02), and persistent bacteremia (27/49 [55.1 %]; adjusted OR, 4.29; 95% Cl, 1.99-9.22; P<.001). Conclusions Prosthetic valve endocarditis accounts for a high percentage of all cases of infective endocarditis in many regions of the world. Staphylococcus aureus is now the leading cause of PVE. Health care-associated infection significantly influences the clinical characteristics and outcome of PVE. Complications of PVE strongly predict in-hospital mortality, which remains high despite prompt diagnosis and the frequent use of surgical intervention.
Affiliations:
- Allemagne, Argentine, Australie, Chili, Espagne, France, Italie, Nouvelle-Zélande, Slovénie, Suède, États-Unis
- Catalogne, Grand Est, Lorraine (région), Région Bretagne, Victoria (État)
- Barcelone, Melbourne, Nancy, Rennes
- Université de Melbourne
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 003D00
- to stream PascalFrancis, to step Curation: 002388
- to stream PascalFrancis, to step Checkpoint: 003995
- to stream Main, to step Merge: 00A107
- to stream Main, to step Curation: 009667
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Contemporary clinical profile and outcome of prosthetic valve endocarditis</title><author><name sortKey="Wang, Andrew" sort="Wang, Andrew" uniqKey="Wang A" first="Andrew" last="Wang">Andrew Wang</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Medicine, Duke University Medical Center</s1><s2>Durham, NC</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Durham, NC</wicri:noRegion></affiliation></author><author><name sortKey="Athan, Eugene" sort="Athan, Eugene" uniqKey="Athan E" first="Eugene" last="Athan">Eugene Athan</name><affiliation wicri:level="4"><inist:fA14 i1="02"><s1>Department of Infectious Disease, The Geelong Hospital at the University of Melbourne</s1><s2>Melbourne</s2><s3>AUS</s3><sZ>2 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Pappas, Paul A" sort="Pappas, Paul A" uniqKey="Pappas P" first="Paul A." last="Pappas">Paul A. Pappas</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Outcomes Research and Assessment Group, Duke Clinical Research Institute</s1><s2>Durham, NC</s2><s3>USA</s3><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Durham, NC</wicri:noRegion></affiliation></author><author><name sortKey="Fowler, Vance G Jr" sort="Fowler, Vance G Jr" uniqKey="Fowler V" first="Vance G. Jr" last="Fowler">Vance G. Jr Fowler</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Medicine, Duke University Medical Center</s1><s2>Durham, NC</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Durham, NC</wicri:noRegion></affiliation></author><author><name sortKey="Olaison, Lars" sort="Olaison, Lars" uniqKey="Olaison L" first="Lars" last="Olaison">Lars Olaison</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Department of Infectious Disease, Sahlgrenska Universitetssjukhuset/ Ostra</s1><s2>Göteborg</s2><s3>SWE</s3><sZ>5 aut.</sZ></inist:fA14><country>Suède</country><wicri:noRegion>Göteborg</wicri:noRegion></affiliation></author><author><name sortKey="Pare, Carlos" sort="Pare, Carlos" uniqKey="Pare C" first="Carlos" last="Pare">Carlos Pare</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Department of Cardiology, University of Barcelona</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>6 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Almirante, Benito" sort="Almirante, Benito" uniqKey="Almirante B" first="Benito" last="Almirante">Benito Almirante</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Infectious Diseases Department, Hospital Universitari Vall d'Hebron</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>7 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Munoz, Patricia" sort="Munoz, Patricia" uniqKey="Munoz P" first="Patricia" last="Munoz">Patricia Munoz</name><affiliation wicri:level="3"><inist:fA14 i1="07"><s1>Department of Infectious Disease, Hospital General Universitario Gregorio Maranon</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>8 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Rizzi, Marco" sort="Rizzi, Marco" uniqKey="Rizzi M" first="Marco" last="Rizzi">Marco Rizzi</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Department of Infectious Disease, Ospedali Riuniti</s1><s2>Bergamo</s2><s3>ITA</s3><sZ>9 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Bergamo</wicri:noRegion></affiliation></author><author><name sortKey="Naber, Christoph" sort="Naber, Christoph" uniqKey="Naber C" first="Christoph" last="Naber">Christoph Naber</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Cardiology Clinic, University Essen</s1><s2>Essen</s2><s3>DEU</s3><sZ>10 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>University Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Logar, Mateja" sort="Logar, Mateja" uniqKey="Logar M" first="Mateja" last="Logar">Mateja Logar</name><affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Department of Infectious Disease, Medical Center Ljublijana</s1><s2>Ljublijana</s2><s3>SVN</s3><sZ>11 aut.</sZ></inist:fA14><country>Slovénie</country><wicri:noRegion>Ljublijana</wicri:noRegion></affiliation></author><author><name sortKey="Tattevin, Pierre" sort="Tattevin, Pierre" uniqKey="Tattevin P" first="Pierre" last="Tattevin">Pierre Tattevin</name><affiliation wicri:level="3"><inist:fA14 i1="11"><s1>Department of Infec tious Disease, Pontchaillou University</s1><s2>Rennes</s2><s3>FRA</s3><sZ>12 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Iarussi, Diana L" sort="Iarussi, Diana L" uniqKey="Iarussi D" first="Diana L." last="Iarussi">Diana L. Iarussi</name><affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Department of Cardiology, II Universita di Napoli</s1><s2>Naples</s2><s3>ITA</s3><sZ>13 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Selton Suty, Christine" sort="Selton Suty, Christine" uniqKey="Selton Suty C" first="Christine" last="Selton-Suty">Christine Selton-Suty</name><affiliation wicri:level="3"><inist:fA14 i1="13"><s1>Cardiology Service, CHU Nancy-Brabois</s1><s2>Nancy</s2><s3>FRA</s3><sZ>14 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Grand Est</region><region type="old region">Lorraine (région)</region><settlement type="city">Nancy</settlement></placeName></affiliation></author><author><name sortKey="Braun Jones, Sandra" sort="Braun Jones, Sandra" uniqKey="Braun Jones S" first="Sandra" last="Braun Jones">Sandra Braun Jones</name><affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Laboratorio de Tecnicas No Invasivas, Hospital Clinico Pont Universidad Catolica de Chile</s1><s2>Santiago</s2><s3>CHL</s3><sZ>15 aut.</sZ></inist:fA14><country>Chili</country><wicri:noRegion>Santiago</wicri:noRegion></affiliation></author><author><name sortKey="Casabe, Jose" sort="Casabe, Jose" uniqKey="Casabe J" first="José" last="Casabe">José Casabe</name><affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Department of Cardiology, Institute de Cardiologia y Cirugia Cardiovascular, Fundacion Favaloro</s1><s2>Buenos Aires</s2><s3>ARG</s3><sZ>16 aut.</sZ></inist:fA14><country>Argentine</country><wicri:noRegion>Buenos Aires</wicri:noRegion></affiliation></author><author><name sortKey="Morris, Arthur" sort="Morris, Arthur" uniqKey="Morris A" first="Arthur" last="Morris">Arthur Morris</name><affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Diagnostic Medlab, Auckland City Hospital</s1><s2>Auckland</s2><s3>NZL</s3><sZ>17 aut.</sZ></inist:fA14><country>Nouvelle-Zélande</country><wicri:noRegion>Auckland</wicri:noRegion></affiliation></author><author><name sortKey="Corey, Ralph" sort="Corey, Ralph" uniqKey="Corey R" first="Ralph" last="Corey">Ralph Corey</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Medicine, Duke University Medical Center</s1><s2>Durham, NC</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Durham, NC</wicri:noRegion></affiliation></author><author><name sortKey="Cabell, Christopher H" sort="Cabell, Christopher H" uniqKey="Cabell C" first="Christopher H." last="Cabell">Christopher H. Cabell</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Medicine, Duke University Medical Center</s1><s2>Durham, NC</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Durham, NC</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">07-0191068</idno><date when="2007">2007</date><idno type="stanalyst">PASCAL 07-0191068 INIST</idno><idno type="RBID">Pascal:07-0191068</idno><idno type="wicri:Area/PascalFrancis/Corpus">003D00</idno><idno type="wicri:Area/PascalFrancis/Curation">002388</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">003995</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">003995</idno><idno type="wicri:doubleKey">0098-7484:2007:Wang A:contemporary:clinical:profile</idno><idno type="wicri:Area/Main/Merge">00A107</idno><idno type="wicri:Area/Main/Curation">009667</idno><idno type="wicri:Area/Main/Exploration">009667</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Contemporary clinical profile and outcome of prosthetic valve endocarditis</title><author><name sortKey="Wang, Andrew" sort="Wang, Andrew" uniqKey="Wang A" first="Andrew" last="Wang">Andrew Wang</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Medicine, Duke University Medical Center</s1><s2>Durham, NC</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Durham, NC</wicri:noRegion></affiliation></author><author><name sortKey="Athan, Eugene" sort="Athan, Eugene" uniqKey="Athan E" first="Eugene" last="Athan">Eugene Athan</name><affiliation wicri:level="4"><inist:fA14 i1="02"><s1>Department of Infectious Disease, The Geelong Hospital at the University of Melbourne</s1><s2>Melbourne</s2><s3>AUS</s3><sZ>2 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region><settlement type="city">Melbourne</settlement></placeName><orgName type="university">Université de Melbourne</orgName></affiliation></author><author><name sortKey="Pappas, Paul A" sort="Pappas, Paul A" uniqKey="Pappas P" first="Paul A." last="Pappas">Paul A. Pappas</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Outcomes Research and Assessment Group, Duke Clinical Research Institute</s1><s2>Durham, NC</s2><s3>USA</s3><sZ>3 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Durham, NC</wicri:noRegion></affiliation></author><author><name sortKey="Fowler, Vance G Jr" sort="Fowler, Vance G Jr" uniqKey="Fowler V" first="Vance G. Jr" last="Fowler">Vance G. Jr Fowler</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Medicine, Duke University Medical Center</s1><s2>Durham, NC</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Durham, NC</wicri:noRegion></affiliation></author><author><name sortKey="Olaison, Lars" sort="Olaison, Lars" uniqKey="Olaison L" first="Lars" last="Olaison">Lars Olaison</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Department of Infectious Disease, Sahlgrenska Universitetssjukhuset/ Ostra</s1><s2>Göteborg</s2><s3>SWE</s3><sZ>5 aut.</sZ></inist:fA14><country>Suède</country><wicri:noRegion>Göteborg</wicri:noRegion></affiliation></author><author><name sortKey="Pare, Carlos" sort="Pare, Carlos" uniqKey="Pare C" first="Carlos" last="Pare">Carlos Pare</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Department of Cardiology, University of Barcelona</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>6 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Almirante, Benito" sort="Almirante, Benito" uniqKey="Almirante B" first="Benito" last="Almirante">Benito Almirante</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Infectious Diseases Department, Hospital Universitari Vall d'Hebron</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>7 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Munoz, Patricia" sort="Munoz, Patricia" uniqKey="Munoz P" first="Patricia" last="Munoz">Patricia Munoz</name><affiliation wicri:level="3"><inist:fA14 i1="07"><s1>Department of Infectious Disease, Hospital General Universitario Gregorio Maranon</s1><s2>Barcelona</s2><s3>ESP</s3><sZ>8 aut.</sZ></inist:fA14><country>Espagne</country><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Rizzi, Marco" sort="Rizzi, Marco" uniqKey="Rizzi M" first="Marco" last="Rizzi">Marco Rizzi</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Department of Infectious Disease, Ospedali Riuniti</s1><s2>Bergamo</s2><s3>ITA</s3><sZ>9 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Bergamo</wicri:noRegion></affiliation></author><author><name sortKey="Naber, Christoph" sort="Naber, Christoph" uniqKey="Naber C" first="Christoph" last="Naber">Christoph Naber</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Cardiology Clinic, University Essen</s1><s2>Essen</s2><s3>DEU</s3><sZ>10 aut.</sZ></inist:fA14><country>Allemagne</country><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>University Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Logar, Mateja" sort="Logar, Mateja" uniqKey="Logar M" first="Mateja" last="Logar">Mateja Logar</name><affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Department of Infectious Disease, Medical Center Ljublijana</s1><s2>Ljublijana</s2><s3>SVN</s3><sZ>11 aut.</sZ></inist:fA14><country>Slovénie</country><wicri:noRegion>Ljublijana</wicri:noRegion></affiliation></author><author><name sortKey="Tattevin, Pierre" sort="Tattevin, Pierre" uniqKey="Tattevin P" first="Pierre" last="Tattevin">Pierre Tattevin</name><affiliation wicri:level="3"><inist:fA14 i1="11"><s1>Department of Infec tious Disease, Pontchaillou University</s1><s2>Rennes</s2><s3>FRA</s3><sZ>12 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Région Bretagne</region><region type="old region">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Iarussi, Diana L" sort="Iarussi, Diana L" uniqKey="Iarussi D" first="Diana L." last="Iarussi">Diana L. Iarussi</name><affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Department of Cardiology, II Universita di Napoli</s1><s2>Naples</s2><s3>ITA</s3><sZ>13 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Naples</wicri:noRegion></affiliation></author><author><name sortKey="Selton Suty, Christine" sort="Selton Suty, Christine" uniqKey="Selton Suty C" first="Christine" last="Selton-Suty">Christine Selton-Suty</name><affiliation wicri:level="3"><inist:fA14 i1="13"><s1>Cardiology Service, CHU Nancy-Brabois</s1><s2>Nancy</s2><s3>FRA</s3><sZ>14 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Grand Est</region><region type="old region">Lorraine (région)</region><settlement type="city">Nancy</settlement></placeName></affiliation></author><author><name sortKey="Braun Jones, Sandra" sort="Braun Jones, Sandra" uniqKey="Braun Jones S" first="Sandra" last="Braun Jones">Sandra Braun Jones</name><affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Laboratorio de Tecnicas No Invasivas, Hospital Clinico Pont Universidad Catolica de Chile</s1><s2>Santiago</s2><s3>CHL</s3><sZ>15 aut.</sZ></inist:fA14><country>Chili</country><wicri:noRegion>Santiago</wicri:noRegion></affiliation></author><author><name sortKey="Casabe, Jose" sort="Casabe, Jose" uniqKey="Casabe J" first="José" last="Casabe">José Casabe</name><affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Department of Cardiology, Institute de Cardiologia y Cirugia Cardiovascular, Fundacion Favaloro</s1><s2>Buenos Aires</s2><s3>ARG</s3><sZ>16 aut.</sZ></inist:fA14><country>Argentine</country><wicri:noRegion>Buenos Aires</wicri:noRegion></affiliation></author><author><name sortKey="Morris, Arthur" sort="Morris, Arthur" uniqKey="Morris A" first="Arthur" last="Morris">Arthur Morris</name><affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Diagnostic Medlab, Auckland City Hospital</s1><s2>Auckland</s2><s3>NZL</s3><sZ>17 aut.</sZ></inist:fA14><country>Nouvelle-Zélande</country><wicri:noRegion>Auckland</wicri:noRegion></affiliation></author><author><name sortKey="Corey, Ralph" sort="Corey, Ralph" uniqKey="Corey R" first="Ralph" last="Corey">Ralph Corey</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Medicine, Duke University Medical Center</s1><s2>Durham, NC</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Durham, NC</wicri:noRegion></affiliation></author><author><name sortKey="Cabell, Christopher H" sort="Cabell, Christopher H" uniqKey="Cabell C" first="Christopher H." last="Cabell">Christopher H. Cabell</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Department of Medicine, Duke University Medical Center</s1><s2>Durham, NC</s2><s3>USA</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>18 aut.</sZ><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Durham, NC</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">JAMA, the journal of the American Medical Association</title><title level="j" type="abbreviated">JAMA j. Am. Med. Assoc.</title><idno type="ISSN">0098-7484</idno><imprint><date when="2007">2007</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">JAMA, the journal of the American Medical Association</title><title level="j" type="abbreviated">JAMA j. Am. Med. Assoc.</title><idno type="ISSN">0098-7484</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Endocarditis</term><term>Evolution</term><term>Heart valve</term><term>Medicine</term><term>Prognosis</term><term>Prosthesis</term><term>Symptomatology</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Prothèse</term><term>Symptomatologie</term><term>Evolution</term><term>Endocardite</term><term>Pronostic</term><term>Valvule cardiaque</term><term>Médecine</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Médecine</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Context Prosthetic valve endocarditis (PVE) is associated with significant mortality and morbidity. The contemporary clinical profile and outcome of PVE are not well defined. Objectives To describe the prevalence, clinical characteristics, and outcome of PVE, with attention to health care-associated infection, and to determine prognostic factors associated with in-hospital mortality. Design, Setting, and Participants Prospective, observational cohort study conducted at 61 medical centers in 28 countries, including 556 patients with definite PVE as defined by Duke University diagnostic criteria who were enrolled in the International Collaboration on Endocarditis-Prospective Cohort Study from June 2000 to August 2005. Main Outcome Measure In-hospital mortality. Results Definite PVE was present in 556 (20.1 %) of 2670 patients with infective endocarditis. Staphylococcus aureus was the most common causative organism (128 patients [23.0%]), followed by coagulase-negative staphylococci (94 patients [16.9%]). Health care-associated PVE was present in 203 (36.5%) of the overall cohort. Seventy-one percent of health care-associated PVE occurred within the first year of valve implantation, and the majority of cases were diagnosed after the early (60-day) period. Surgery was performed in 272 (48.9%) patients during the index hospitalization. In-hospital death occurred in 127 (22.8%) patients and was predicted by older age, health care-associated infection (62/203 [30.5%]; adjusted odds ratio [OR], 1.62; 95% confidence interval [Cl], 1.08-2.44; P=.02), S aureus infection (44/128 [34.4%]; adjusted OR, 1.73; 95% Cl, 1.01-2.95; P=.05), and complications of PVE, including heart failure (60/183 [32.8%]; adjusted OR, 2.33; 95% Cl, 1.62-3.34; P<.001), stroke (34/101 [33.7%]; adjusted OR, 2.25; 95% Cl, 1.25-4.03; P=.007), intracardiac abscess (47/144 [32.6%]; adjusted OR, 1.86; 95% Cl, 1.10-3.15; P=.02), and persistent bacteremia (27/49 [55.1 %]; adjusted OR, 4.29; 95% Cl, 1.99-9.22; P<.001). Conclusions Prosthetic valve endocarditis accounts for a high percentage of all cases of infective endocarditis in many regions of the world. Staphylococcus aureus is now the leading cause of PVE. Health care-associated infection significantly influences the clinical characteristics and outcome of PVE. Complications of PVE strongly predict in-hospital mortality, which remains high despite prompt diagnosis and the frequent use of surgical intervention.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Argentine</li><li>Australie</li><li>Chili</li><li>Espagne</li><li>France</li><li>Italie</li><li>Nouvelle-Zélande</li><li>Slovénie</li><li>Suède</li><li>États-Unis</li></country><region><li>Catalogne</li><li>Grand Est</li><li>Lorraine (région)</li><li>Région Bretagne</li><li>Victoria (État)</li></region><settlement><li>Barcelone</li><li>Melbourne</li><li>Nancy</li><li>Rennes</li></settlement><orgName><li>Université de Melbourne</li></orgName></list><tree><country name="États-Unis"><noRegion><name sortKey="Wang, Andrew" sort="Wang, Andrew" uniqKey="Wang A" first="Andrew" last="Wang">Andrew Wang</name></noRegion><name sortKey="Cabell, Christopher H" sort="Cabell, Christopher H" uniqKey="Cabell C" first="Christopher H." last="Cabell">Christopher H. Cabell</name><name sortKey="Corey, Ralph" sort="Corey, Ralph" uniqKey="Corey R" first="Ralph" last="Corey">Ralph Corey</name><name sortKey="Fowler, Vance G Jr" sort="Fowler, Vance G Jr" uniqKey="Fowler V" first="Vance G. Jr" last="Fowler">Vance G. Jr Fowler</name><name sortKey="Pappas, Paul A" sort="Pappas, Paul A" uniqKey="Pappas P" first="Paul A." last="Pappas">Paul A. Pappas</name></country><country name="Australie"><region name="Victoria (État)"><name sortKey="Athan, Eugene" sort="Athan, Eugene" uniqKey="Athan E" first="Eugene" last="Athan">Eugene Athan</name></region></country><country name="Suède"><noRegion><name sortKey="Olaison, Lars" sort="Olaison, Lars" uniqKey="Olaison L" first="Lars" last="Olaison">Lars Olaison</name></noRegion></country><country name="Espagne"><region name="Catalogne"><name sortKey="Pare, Carlos" sort="Pare, Carlos" uniqKey="Pare C" first="Carlos" last="Pare">Carlos Pare</name></region><name sortKey="Almirante, Benito" sort="Almirante, Benito" uniqKey="Almirante B" first="Benito" last="Almirante">Benito Almirante</name><name sortKey="Munoz, Patricia" sort="Munoz, Patricia" uniqKey="Munoz P" first="Patricia" last="Munoz">Patricia Munoz</name></country><country name="Italie"><noRegion><name sortKey="Rizzi, Marco" sort="Rizzi, Marco" uniqKey="Rizzi M" first="Marco" last="Rizzi">Marco Rizzi</name></noRegion><name sortKey="Iarussi, Diana L" sort="Iarussi, Diana L" uniqKey="Iarussi D" first="Diana L." last="Iarussi">Diana L. Iarussi</name></country><country name="Allemagne"><noRegion><name sortKey="Naber, Christoph" sort="Naber, Christoph" uniqKey="Naber C" first="Christoph" last="Naber">Christoph Naber</name></noRegion></country><country name="Slovénie"><noRegion><name sortKey="Logar, Mateja" sort="Logar, Mateja" uniqKey="Logar M" first="Mateja" last="Logar">Mateja Logar</name></noRegion></country><country name="France"><region name="Région Bretagne"><name sortKey="Tattevin, Pierre" sort="Tattevin, Pierre" uniqKey="Tattevin P" first="Pierre" last="Tattevin">Pierre Tattevin</name></region><name sortKey="Selton Suty, Christine" sort="Selton Suty, Christine" uniqKey="Selton Suty C" first="Christine" last="Selton-Suty">Christine Selton-Suty</name></country><country name="Chili"><noRegion><name sortKey="Braun Jones, Sandra" sort="Braun Jones, Sandra" uniqKey="Braun Jones S" first="Sandra" last="Braun Jones">Sandra Braun Jones</name></noRegion></country><country name="Argentine"><noRegion><name sortKey="Casabe, Jose" sort="Casabe, Jose" uniqKey="Casabe J" first="José" last="Casabe">José Casabe</name></noRegion></country><country name="Nouvelle-Zélande"><noRegion><name sortKey="Morris, Arthur" sort="Morris, Arthur" uniqKey="Morris A" first="Arthur" last="Morris">Arthur Morris</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 009667 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 009667 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= Pascal:07-0191068
|texte= Contemporary clinical profile and outcome of prosthetic valve endocarditis
}}
| This area was generated with Dilib version V0.6.33. |  |